Most items in Wyvern can be cursed by being hit with the curse spell, or having a player cast the Curse spell. Some items can also be found cursed. The curse on an item can be lifted by using a Uncurse Altar, for a small fee.
Cursing an item brings a couple negative effects. For instance, cursed equipment cannot be unequipped, and cursed potions and scrolls are less effective and wear off quickly.